Tuesday, November 29, 2011

Granulomatous Mastitis (Fungal)

40 years old, Bangali Female patient, has many discharging breast sinuses. Received breast tissue shows multiple cutaneous sinuses, and cut section shows many irregular brownish cavitations oozing yellowish material. Microscopically shows non-caseating epithelioid granulomas with lympho-plasmacytic infiltrate and focal central neutrophilic collection as well as scattered multinucleated giant cells. ZN stain was negative for AFB. PAS stain shows positive needle-shaped bodies within the center of some granulomas ; suggestive of Actinomycosis.











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