Tuesday, April 19, 2011

Cervical lymphadenopathy

Male patient, 55 YO, with moderately enlarged cervical lymph nodes, firm> No hepatic or splenic enlargement by sonar and showing recent gradual weight loss.
Received multiple LNs; the largest 2.5 cm in diameter with grayish cut surface.
Microscopically; loss of architecture, infiltration by groups of large cells with vesicular nuclei and prominent nucleoli, scattered mitoses, irregular fibrosis and plasma-lymphocytic infiltration. (DD;sarcomatoid variant of ALCL; follicular dendretic lymphoma, inflammatory pseudotumor, ....OTHERs. Plz, what are ur suggestions and recommended markers.Thanks.